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Illinois Clinical Trials – Pleural Mesothelioma

Illinois Clinical Trials for Pleural Mesothelioma

 

1. University of Chicago (Chicago, IL)

 
Name of Study:
A Phase Ib Trial of a Maintenance Multipeptide Vaccine (S-588210) in Patients With Unresectable Malignant Pleural Mesothelioma Without Progression After First-Line Chemotherapy

Study type:
Interventional

Purpose:
To give S-588210 –peptide vaccine in mpm patients without progression of disease after receiving chemotherapy

ClinicalTrials.gov Identifier:
NCT02661659

Status:
Currently recruiting February 2016- February 2018 Estimated enrollment 16 participants

Location:
University of Chicago

Contact:
Rose Buerkley
773-834-4002
brose@bsd.uchicago.edu

Mewish Ahmad
773-834-1472
mahmad3@medicine.bsd.uchicago.edu

 

2. University of Chicago (Chicago, IL)

 
Name of Study:
A Pilot Window of Opportunity Study of the Anti-PD-1 Antibody Pembrlizumab in Patients With Resectable Malignant Pleural Mesothelioma

Study type:
Interventional

Purpose:
Patients will undergo a pretreatment PET/CT scan for clinical staging and a VATS procedure to acquire pretreatment tissue. Three cycles of Pembrolizmab will be given and another PET/CT scan to assess response. Surgical resection will take place 4 weeks after third dose of chemotherapy given. Standard chemotherapy will be given 6-8 weeks after surgery after another CT scan. Ct scans will be done every 2 cycles of chemotherapy in evaluate response. After chemotherapy is finished optional pembrolzumab will be given to eligible patients for 1-year post surgery.

ClinicalTrials.gov Identifier:
NCT02707666

Status:
Currently recruiting February 2016 – March 2018 – Estimated enrollment 15 participants

Location:
University of Chicago

Contact:
Rose Buerkley
773-834-4002
brose@bsd.uchicago.edu

Mewish Ahmad
773-834-1472
mahmad3@medicine.bsd.uchicago.edu

 

3. University of Chicago (Chicago, IL)

 
Name of Study:
Pembrolizumab in Treating Patients With Malignant Mesothelioma

Study type:
Interventional

Purpose:
This Phase ll trial studies how well pembrolizumab works in treating patients with malignant mesothelioma, a cancer of the linings around the lungs (pleura) or abdomen (peritoneum). Monoclonal antibodies, such as pembrolizumab, work by blocking a protein called programmed cell death l (PD-l) which may stimulate an immune response and kill tumor cells

ClinicalTrials.gov Identifier:
NCT02399371

Status:
Enrolling- Start date March 2015 Completion date March 2018; Estimated enrollment 65

Location:
University of Chicago, Chicago Illinois 60637

Contact:
Hedy L. Kindler
773-702-0360
hkindler@medicine.bsd.uchicago.edu

 

Mesothelioma Clinical Trial Information

 

Learn More About Mesothelioma

 

Did You Know?

  • Mesothelioma Facts
    Mesothelioma Facts
    The highest award of compensatory damages ever upheld on appeal in a mesothelioma case is $30.3 million.
  • Mesothelioma Facts
    Mesothelioma Facts
    The largest punitive damages verdict ever upheld on appeal in a mesothelioma case is $18 million.
  • Mesothelioma Facts
    Mesothelioma Facts
    There are over $30 billion in asbestos trust funds to compensate victims of mesothelioma and other asbestos-related diseases.
  • Mesothelioma Facts
    Mesothelioma Facts
    There are more than 50 bankruptcy trusts accepting claims to compensate victims of mesothelioma and other asbestos-related diseases.
  • Mesothelioma Facts
    Mesothelioma Facts
    There are many “asbestos dockets” that permit living mesothelioma patients to obtain a jury verdict in less than 1 year.
  • Mesothelioma Facts
    Mesothelioma Facts
    In 2015, more than 2000 mesothelioma cases were filed in the United States.
  • Mesothelioma Facts
    Mesothelioma Facts
    In some mesothelioma cases, settlements can be obtained in less than 1 year.
  • Mesothelioma Facts
    Mesothelioma Facts
    Thousands of different companies have been defendants in mesothelioma cases over the past 40 years.
  • Mesothelioma Facts
    Mesothelioma Facts
    According to a 2015 study of 77 peritoneal mesothelioma cases, the average life expectancy (median survival period) was 75.7 months, or over 6 years.
  • Mesothelioma Facts
    Mesothelioma Facts
    According to a 2015 study of 77 peritoneal mesothelioma patients, 73.8% were living after 3 years, and 65.3% were living after 5 years.
  • Mesothelioma Facts
    Mesothelioma Facts
    According to a 2015 study of 77 peritoneal mesothelioma patients, 64% were treated with HIPEC and cytoreductive surgery.
  • Mesothelioma Facts
    Mesothelioma Facts
    According to a 2015 study of 303 pleural mesothelioma patients, the average life expectancy (median survival period) was 18.4 months.
  • Mesothelioma Facts
    Mesothelioma Facts
    According to a 2015 study of pleural mesothelioma patients, 73.1% were still living after 1 year, and 22.9% were still living after 3 years.
  • Mesothelioma Facts
    Mesothelioma Facts
    In 2015, the largest number of mesothelioma cases were filed in the following 10 courts: (1) Madison County, IL; (2) Cook County, IL; (3) St. Louis, MO; (4) Los Angeles, CA; (5) New York, NY; (6) Philadelphia, PA; (7) New Castle County, DE; (8) Middlesex County, MA; (9)Middlesex County, NJ; (10) Kanawha County, WV.
  • Mesothelioma Facts
    Mesothelioma Facts
    The states with the largest number of diagnosed mesothelioma cases are: New York, New Jersey, California, Washington, Pennsylvania, Massachusetts, Virginia, Florida, Texas, Illinois, Wisconsin, Michigan and Ohio.
  • Mesothelioma Facts
    Mesothelioma Facts
    There are about 3000 mesothelioma cases diagnosed in the United States each year.
  • Mesothelioma Facts
    Mesothelioma Facts
    About 1 in 100,000 people in the United States will be diagnosed with mesothelioma each year in the United States.
  • Mesothelioma Facts
    Mesothelioma Facts
    More than 80% of all mesothelioma cases occur in the pleura (pleural mesothelioma).
  • Mesothelioma Facts
    Mesothelioma Facts
    Less than 20% of all mesothelioma cases occur in the peritoneum (peritoneal mesothelioma).
  • Mesothelioma Facts
    Mesothelioma Facts
    About 22% of all mesothelioma cases occur in women.
  • Mesothelioma Facts
    Mesothelioma Facts
    A history of asbestos exposure can be found in more than 80% of mesothelioma cases.
  • Mesothelioma Facts
    Mesothelioma Facts
    More than 30% of all mesothelioma patients in the United States were exposed to asbestos in the military.
  • Mesothelioma Facts
    Mesothelioma Facts
    Mesothelioma can be caused by laundering, or other household contact with, work clothing contaminated with asbestos.
  • Mesothelioma Facts
    Mesothelioma Facts
    Mesothelioma can be caused by work with (direct exposure) or around (bystander exposure) asbestos-containing products.
  • Mesothelioma Facts
    Mesothelioma Facts
    The average time between a person’s first exposure to asbestos and the development of mesothelioma (latency period) is more than 40 years.
 

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